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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1A
All Species:
23.94
Human Site:
T40
Identified Species:
37.62
UniProt:
P10644
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10644
NP_002725.1
381
42982
T40
D
S
I
V
Q
L
C
T
A
R
P
E
R
P
M
Chimpanzee
Pan troglodytes
XP_511647
260
29299
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537577
381
43019
T40
D
S
I
V
Q
L
C
T
A
R
P
E
R
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBC7
381
43167
T40
D
S
I
V
Q
L
C
T
T
R
P
E
R
P
M
Rat
Rattus norvegicus
P09456
381
43076
T40
D
S
I
V
Q
L
C
T
A
R
P
E
R
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
T179
D
C
I
V
Q
L
C
T
S
R
P
E
R
P
M
Chicken
Gallus gallus
Q5ZM91
382
43332
T40
D
C
I
V
Q
L
C
T
V
R
P
D
R
P
M
Frog
Xenopus laevis
NP_001085084
381
43157
V40
C
I
V
Q
L
C
T
V
R
P
A
C
P
M
A
Zebra Danio
Brachydanio rerio
NP_001017732
379
43009
S40
C
I
V
Q
L
C
T
S
R
P
D
R
P
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
E43
Q
L
C
V
C
R
P
E
N
P
V
Q
F
L
R
Honey Bee
Apis mellifera
XP_396167
372
41646
S44
G
R
P
E
N
P
I
S
F
L
R
E
Y
F
Q
Nematode Worm
Caenorhab. elegans
P30625
366
41449
N40
L
C
I
H
K
P
D
N
P
V
L
F
L
K
D
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G48
E
N
N
I
S
L
G
G
K
R
G
V
T
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
V60
E
F
K
A
K
N
I
V
L
F
P
E
P
E
E
Red Bread Mold
Neurospora crassa
Q01386
385
42138
T44
D
T
I
T
S
P
T
T
P
H
F
G
V
K
N
Conservation
Percent
Protein Identity:
100
68.2
N.A.
97.9
N.A.
96.8
97.3
N.A.
58.7
92.4
92.6
91.5
N.A.
71.3
74
57.7
39.3
Protein Similarity:
100
68.2
N.A.
98.1
N.A.
97.3
98.4
N.A.
60
96
95.8
95.8
N.A.
81.6
85.3
73.4
56.9
P-Site Identity:
100
0
N.A.
100
N.A.
93.3
100
N.A.
86.6
80
0
0
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
0
N.A.
100
N.A.
93.3
100
N.A.
93.3
86.6
6.6
13.3
N.A.
13.3
13.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
34
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
20
0
7
0
0
0
14
% A
% Cys:
14
20
7
0
7
14
40
0
0
0
0
7
0
0
0
% C
% Asp:
47
0
0
0
0
0
7
0
0
0
7
7
0
0
7
% D
% Glu:
14
0
0
7
0
0
0
7
0
0
0
47
0
7
7
% E
% Phe:
0
7
0
0
0
0
0
0
7
7
7
7
7
14
0
% F
% Gly:
7
0
0
0
0
0
7
7
0
0
7
7
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
14
54
7
0
0
14
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
14
0
0
0
7
0
0
0
0
14
0
% K
% Leu:
7
7
0
0
14
47
0
0
7
7
7
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
40
% M
% Asn:
0
7
7
0
7
7
0
7
7
0
0
0
0
0
7
% N
% Pro:
0
0
7
0
0
20
7
0
14
20
47
0
20
40
0
% P
% Gln:
7
0
0
14
40
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
7
0
0
0
7
0
0
14
47
7
7
40
0
7
% R
% Ser:
0
27
0
0
14
0
0
14
7
0
0
0
0
0
0
% S
% Thr:
0
7
0
7
0
0
20
47
7
0
0
0
7
0
7
% T
% Val:
0
0
14
47
0
0
0
14
7
7
7
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _